Summit4StemCell

Profile of this project:

Uses the patient's own skin cells, which are retro-developed back into stem cells (so-called induced pluripotent stem cells, iPSC) and then grown into dopamine-producing neurons.
Since the neurons to be transplanted are originally derived from the respective patient him- or herself, no rejection by the immune system is expected.
The necessary basic research as well as a large part of the required animal experiments have been successfully completed by the project team. Therefore the poject is likely to enter the clinical approval test in humans phase after completion of the last animal experiments still needed.
The project has successfully completed the necessary basic research as well as a large part of the required animal experiments and is likely to enter the phase of the clinical approval test in humans after completion of the last animal experiments which are still necessary.
Provided the clinical approval test is successful, an effective procedure to restore the function of the substantia nigra could be made available in the foreseeable future.
The sponsor of the research project is the "Summit4StemCell" non-profit initiative from San Diego (USA), which is mainly financed by donations from affected persons.

The non-profit initiative expects to need additional millions of USD for the remaining animal tests still required by the US regulatory authority FDA and the subsequent clinical trial of human beings. Of these, it has already invested more than $ 2.7 million of private donations (including those collected by our Förderverein Parkinson-Heilung e.V.). After almost 2 years of application, the CIRM (the funding agency of the federal state of California) has granted funding at the level of US$ 2.36 million in July 2016. In order to be able to carry out the necessary research work before the start of the clinical trials, however, approximately another $ 4.5 million is needed.

Since this project is very promising and also very advanced, the Förderverein Parkinson-Heilung e.V., that runs this webiste, supports it actively with its current request for donations.

The Summit for Stem Cell Foundation, the Scripps Clinic of San Diego (Neurology), and the Scripps Research Institute (Stem Cell Research), jointly run the non-profit initiative called "Summit4StemCell".
Further information about this project:

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